Welcome to the Otwinowski Lab



The main research focus of the Otwinowski lab is on developing computational and statistical
methods and protocols for macromolecular structure determination using X-ray crystallography.

We have been contributing to the:

  • scaling and merging of data
  • model building and refinement
  • core algorithms
  • lab automation techniques

Our group is also interested in:

  • analysis of whole-genome gene expression data
  • transcriptional regulation of the cell division cycle
  • spatial organization of chromatin
  • molecular evolution

Part of our research is conducted within the MCSG.

Otwinowski Lab / Department of Biochemistry / UTSouthwestern Medical Center
Address: 5323 Harry Hines Boulevard, Room ND10.214, Dallas, TX 75390-8816
Phone: +1 (214) 645-6378 / Fax: +1 (214) 645-6353
E-mail: zbyszek.otwinowski@utsouthwestern.edu